Why cells need iron
Why cells need iron: a compendium of iron utilisation Author links open overlay panel Megan R. Teh 1 , Andrew E. Armitage 1 , Hal Drakesmith 1 Show more Add to Mendeley Share Cite https://doi.org/10.1016/j.tem.2024.04.015 Get rights and content Under a Creative Commons license open access Highlights Iron has a key role in multiple important cellular processes, including gene regulation, metabolism, bioenergetics, and hormone synthesis. Iron deficiency is globally widespread and associated with several and diverse impacts on health, the underlying mechanisms of which are poorly understood. We describe potential molecular causative links between cellular iron deficiency and a range of symptoms, and indicate important unknowns in the field. Abstract Iron deficiency is globally prevalent, causing an array of developmental, haematological, immunological, neurological, and cardiometabolic impairments, and is associated with sy...